Endocrine Abstracts

BackgroundPheochromocytomas are rare tumors originating from chromaffin cells and characterized by excessive catecholamine synthesis. They are usually benign lesions. Hypertension(HT), tachycardia, sweating and headache are frequently observed. We aimed to present a high malignancy suspected pheochromocytoma case diagnosed in a young age female.Case presentationA 20-year-old female patient was admitted to the...

Objective: Even with advancements in diagnostic techniques, acromegaly continues to be diagnosed late. This study aimed to employ deep learning methods to automatically identify acromegaly disease from images of faces, hands, and feet to enhance the efficiency of disease detection.Design: Cross-sectionaly single-center study with deep learningMethods: The study included 71 acromegaly patients and 65 healthy controls. All patients h...

Objective: In differentiated thyroid carcinoma (DTC), TSH suppression with levothyroxine (L-T4) is a standard treatment for reducing tumor recurrence after total thyroidectomy. This study aims to evaluate the effect of long-term TSH suppression on the development of sarcopenia and frailty in elderly patients with DTC.Method: Seventy patients aged 60 years and older with stable TSH levels during the last year and under L-T4 due to DTC were included in the...

Introduction: Recently, Programmed cell death ligand 1 (PD-L1) inhibitors have been frequently used as promising treatment options for some advanced malignancies. Although immune-related side effects secondary to PD-1 inhibitor treatment are well defined in the literature, data on PD-L1 inhibitors are limited. Thyroid dysfunction was reported in 10% of patients in the clinical study of atezolizumab. We aimed to present a case of severe hypothyroidism-related rhabdomyolysis and...

Background: Anxiety level is higher in the samples consisting of people diagnosed with pituitary adenoma, including patients with acromegaly, compared to the normal population. A higher level of anxiety indicates a lower Quality of Life (QoL) in acromegaly. This study aimed to evaluate and discuss the possible relationship between anxiety and NS in people with acromegaly.Method: This cross-sectional comparative study included an acromegaly group (AG, <em...

Aim: Metabolic syndrome rates have been studied especially in adrenal gland secreting cortisol and studies on nonfunctional adenomas are limited. In this study, we investigated metabolic parameters and metabolic syndrome frequency in non-functional adrenal adenomas (NFA).Materials and methods: In our study, 55 patients (15 men (27.3%), 40 women (72.7%) who were diagnosed incidentally, unilateral or bilateral localized, hormone-inactive, and with adenoma-...

Introduction: Hyperkalemia due to zona glomerulosa (ZG) insufficiency is generally transient and mild for patients with aldosterone-producing adenoma (APA) after adrenalectomy. We report here a case with prolonged ZG insuffiency requiring long-term mineralocorticoid replacement (MR) therapy.Case report: A 45-years-old female with hypertension and hypokalemia admitted to outpatient clinic with incidentally detected right adrenal adenoma (3 cm) showing sig...

Background: Primary hyperparathyroidism (PHPT) is one of the most common endocrine diseases. Parathyroid carcinoma, a rare entity, comprises a small percentage of patients with hyperparathyroidism and represents 0.005% of all cancers and <1% of cases of PHPT.Material and methods: Patients was diagnosed at the Endocrinology Department of Diskapi Yildirim Beyazit Training and Research Hospital between 2010 and 2016. Ultrasound and 99mTc-Sestamibi confi...

Introduction: Hypogonadism persisting in man with macroprolactinoma requires exogenous testosterone replacement therapy (TRT). But TRT may cause secondary elevations of prolactin. We report here a case of macroprolactinoma and hypogonadotropic hypogonadism with persistently high prolactin level after initiating TRT.Case report: A 28 year-old male was admitted to outpatient clinic with complaints of headache, low libido and blurred vision on left eye for ...

Background and aim: The risk for breast cancer in patients with thyroid cancer has been investigated in previous studies, and has been found to be increased. In this study we, therefore present retrospective analysis of the patients with differentiated thyroid carcinoma in respect to breast cancer and family history for breast cancer.Methods: We conducted a retrospective study involving 455 patients with a diagnosis of differentiated thyroid carcinoma be...